How to read a peptide certificate of analysis
A practical guide to checking a peptide COA: match the sample, separate identity from purity and content, and read each result against its stated limit.
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Research Hub
Find compound identities, names and chemistry, understand peptide testing, and check the documents supplied with UK research orders.
47 articles to explore
What are research peptides? Identity, sequences and certificates
What a research peptide is, how its sequence identifies it, and which product and certificate details to compare before ordering in the UK.
Read the article →Research use only (RUO): reading peptide labels
Understand research use only on a peptide label and compare the stated material, specification and lot certificate without filling gaps from the abbreviation.
Read the article →How to read a peptide sequence on a specification
Read peptide sequence letters, terminal groups, D/L notation and fragment numbers, with a GHK example and links to the matching product and certificate.
Read the article →Peptide molecular formula, molecular weight and mass explained
Compare peptide formula, molecular weight, Da, g/mol and LC-MS mass. Keep the molecular structure and salt basis separate from the vial amount.
Read the article →Peptide CAS numbers: checking identity against a certificate
Use a peptide CAS number alongside its sequence, declared form and lot certificate. Learn which identifiers describe the substance and which describe the report.
Read the article →Peptide acetate and TFA salts: reading the specification
Distinguish acetate or TFA counterions from acetyl modifications, and read the declared salt, residual-ion limit and measured lot composition separately.
Read the article →What does lyophilised peptide mean? Freeze-dried material explained
Lyophilised means freeze-dried. Check the documented form, appearance, residual water and storage evidence separately when reading a peptide specification.
Read the article →Peptide HPLC purity testing: how to read the percentage
Understand HPLC area purity, chromatogram peaks, detector response and reporting limits, using the supplied Semax certificate as a worked example.
Read the article →LC-MS and LC-MS/MS peptide identity testing explained
Read peptide mass-to-charge labels and understand what intact mass, fragmentation and a reported identity result can establish about a sample.
Read the article →Peptide sterility testing: reading a no-growth result
Read the method, sampled amount, recovery checks and incubation dates behind a peptide sterility result, and distinguish it from bioburden testing.
Read the article →Peptide endotoxin testing: LAL, rFC and certificate results
Understand peptide endotoxin test formats, EU units, less-than results and sample interference, with questions to ask about the method behind a certificate.
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