Ipamorelin peptide: sequence and certificate identity

Read ipamorelin’s five-residue sequence, including Aib, D-2-Nal, D-Phe and terminal amidation, and check the identity fields in its batch certificate.

Substantially revised on 3 October 2026 to focus on molecular identity, naming, chemistry, testing and batch documentation.

Ipamorelin is a five-residue peptide written Aib–His–D-2-Nal–D-Phe–Lys–NH2. The non-standard residues, D designations and amidated terminus are part of the molecular identity and should remain in a specification.

Read the complete ipamorelin sequence

Raun and colleagues identify ipamorelin as the pentapeptide Aib–His–D-2-Nal–D-Phe–Lys–NH2. Aib and D-2-Nal are retained in their original notation here; reducing the chain to ordinary one-letter amino-acid codes would lose information.Raun et al. (1998) (opens in a new tab)

Ipamorelin identity record
FieldDocumented detail
NameIpamorelin
SequenceAib–His–D-2-Nal–D-Phe–Lys–NH2
Residue count5
Stereochemical notationD-2-Nal and D-Phe are explicitly specified
C terminusAmidated, written NH2
CAS number170851-70-4 (PubChem registry number for ipamorelin). The supplied report does not print a CAS number.
Formula and molecular weightNot established by the cited sequence passage or supplied report
Raun et al. (1998) (opens in a new tab)Supplied Ipamorelin 5 mg report — lot IPA-25-6RT (opens in a new tab)

Ipamorelin and ghrelin are different molecules

The ghrelin discovery paper describes a 28-residue peptide with an n-octanoyl group on serine 3, and records species sequence differences. That chain and modification are different from ipamorelin’s five-residue sequence. Ghrelin is therefore a separate identity reference, not a synonym or longer spelling of ipamorelin.Kojima et al. (1999) (opens in a new tab)Raun et al. (1998) (opens in a new tab)

Connect the sequence record to the batch document

The supplied 5 mg ipamorelin report describes a synthetic freeze-dried pentapeptide and an LC-HRMS comparison with a qualified reference. It does not print the full sequence or a complete salt specification. Keep the published sequence distinct from the report’s actual wording when asking for the reference specification.Supplied Ipamorelin 5 mg report — lot IPA-25-6RT (opens in a new tab)Raun et al. (1998) (opens in a new tab)

The report gives chromatographic area purity, measured ipamorelin content, water and residual TFA as separate results. Retain their units and the lot identifier when comparing documents; the area percentage is not the stated mass of ipamorelin per vial.Supplied Ipamorelin 5 mg report — lot IPA-25-6RT (opens in a new tab)

Product and certificate documents

Sources and further detail

  1. Raun et al. (1998) (opens in a new tab)

    Original abstract rechecked for the complete five-residue notation and amidated terminus only.

  2. Kojima et al. (1999) (opens in a new tab)

    Existing ghrelin dossier: residue count, serine-3 acylation and species sequence distinction only.

  3. Supplied Ipamorelin 5 mg report — lot IPA-25-6RT (opens in a new tab)

    Supplied report: identity wording and analytical fields. Results concern the named sample and lot; this is document transcription, not independent authentication.

Identity sources and supplied documents checked for this revision on 3 October 2026. Report transcription is separate from independent authentication. This article has not undergone independent scientific peer review.

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