Explore peptide science, analytical testing and the documentation behind research materials.
Separate molecular identity from organised assemblies, read evidence across structural scales, and distinguish self-assembly from an unsupported interpretation of cloudiness or precipitation.
Read the article →Interpret short sequence-pattern matches as hypotheses, distinguish curated motif instances from predictions, and understand why context is needed before assigning function.
Read the article →Identify an N-terminal acetyl group, distinguish it from acetate and side-chain acetylation, and interpret the associated chemical and mass changes.
Read the article →Read C-terminal amide notation, distinguish it from side-chain amides and deamidation, and interpret the small negative mass change correctly.
Read the article →Identify the lipid, attachment site and linker in a lipidated peptide, and understand why lipidation is a family of chemical structures rather than one predictable effect.
Read the article →Read PEG attachment, chain length and dispersity, and distinguish a defined conjugate from a mixture with variable polymer sizes or attachment sites.
Read the article →Distinguish phosphorylation sites, phosphate counts and site occupancy, and understand why an intact mass cannot always identify the modified residue.
Read the article →Read both the peptide and carbohydrate portions of a glycopeptide, including attachment sites, glycan composition, connectivity and unresolved structural variation.
Read the article →Identify the complete fluorescent peptide conjugate and understand why dye position, linkage and probe integrity matter when interpreting a signal.
Read the article →Understand biotin as an attached affinity tag, distinguish direct attachment from linkered conjugates, and interpret capture without confusing it with peptide-target binding.
Read the article →Interpret isotope substitution, label position and exact mass differences, while separating isotope enrichment from chemical purity and analytical calibration.
Read the article →Read the chemistry and positions of a peptide staple, distinguish conformational constraint from a measured structure, and avoid assuming improved binding or efficacy.
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