Thymosin Alpha 1: thymalfasin sequence, CAS and identity

Find the Thymosin Alpha 1 sequence, thymalfasin synonym, CAS number, molecular formula and weight, and distinguish alpha-1 from beta-4 naming.

Substantially revised on 3 October 2026 to focus on molecular identity, naming, chemistry, testing and documentation.

Thymosin Alpha 1, also called thymalfasin, is an N-acetylated 28-residue peptide. The alpha-1 designation is part of the identity: it should not be shortened to an unspecified thymosin name on a material record.

Thymalfasin reference identity

PubChem connects thymalfasin with Thymosin Alpha 1 and records the N-acetylated structure below. The supplied report describes an N-acetylated 28-residue peptide, but does not print its complete sequence. The database and certificate fields should remain distinguishable.PubChem: Thymalfasin, CID 16130571 (opens in a new tab)Thymosin alpha-1 5 mg report: MA-TA1-0044 (opens in a new tab)

Defined peptide reference
FieldReference or document detail
NamesThymosin Alpha 1; thymosin alpha-1; thymalfasin
CAS for the reference peptide62304-98-7
SequenceAc-SDAAVDTSSEITTKDLKEKKEVVEEAEN-OH
Residues28
Molecular formulaC129H215N33O55
Molecular weight3108.3 g/mol, reference peptide
Sample chemical formFull counterion or hydration specification is not printed in the report
PubChem: Thymalfasin, CID 16130571 (opens in a new tab)Thymosin alpha-1 5 mg report: MA-TA1-0044 (opens in a new tab)

Alpha-1 and beta-4 are separate identity trails

The existing NCBI records identify PTMA as prothymosin alpha and TMSB4X as thymosin beta-4. The historical prothymosin-alpha isolation paper places the alpha-1 sequence at the amino-terminal region of the larger material. These records separate the two naming trails rather than treating the alpha and beta designations as interchangeable.NCBI Gene: PTMA, record 5757 (opens in a new tab)NCBI Gene: TMSB4X, record 7114 (opens in a new tab)Haritos et al. (1984), PMID 6583693 (opens in a new tab)

The original alpha-1 isolation paper also distinguishes the isolated 28-residue component from thymosin fraction 5, the mixture from which it was separated. A mixture name is not a complete identity for one constituent.Goldstein et al. (1977), PMID 265536 (opens in a new tab)

Connect the reference to the batch document

Report MA-TA1-0044, revision 01, identifies lot TA1-44-UWE and gives LC-HRMS reference matching. Its printed N-acetylated 28-residue description is useful, but a full reference specification is still needed to reproduce every structural detail.Thymosin alpha-1 5 mg report: MA-TA1-0044 (opens in a new tab)

Keep the lot, report revision and stated chemical form alongside the sequence reference. The report’s measured content, 5.00 mg, and chromatographic area percentage, 99.33%, belong to the identified sample and should retain their original labels.Thymosin alpha-1 5 mg report: MA-TA1-0044 (opens in a new tab)

Product and certificate checks

Sources and further detail

  1. Thymosin alpha-1 5 mg report: MA-TA1-0044 (opens in a new tab)

    Supplied PDF re-read on 3 October 2026. Identity wording and document-specific results are transcribed; this is not independent authentication.

  2. PubChem: Thymalfasin, CID 16130571 (opens in a new tab)

    Existing primary identity record rechecked through PubChem formula, molecular-weight and synonym data on 3 October 2026. Salt-name synonyms are not treated as identical formula representations.

  3. Goldstein et al. (1977), PMID 265536 (opens in a new tab)

    Existing dossier used for residue count and the isolated-component versus mixture distinction.

  4. NCBI Gene: PTMA, record 5757 (opens in a new tab)

    Existing donor identity source for the prothymosin-alpha naming trail.

  5. NCBI Gene: TMSB4X, record 7114 (opens in a new tab)

    Existing donor identity source for the separate beta-4 naming trail.

  6. Haritos et al. (1984), PMID 6583693 (opens in a new tab)

    Existing donor source used only for the precursor-sequence relationship.

Revised 3 October 2026 using the existing source dossier and the specified primary identity records. Report values describe the linked samples. Products are for laboratory research use only.

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