PT-141 and bremelanotide: sequence and molecular identity

Connect PT141, PT-141 and bremelanotide through the cyclic peptide structure, terminal groups, molecular formula and supplied certificate.

Substantially revised on 3 October 2026 to focus on molecular identity, naming, chemistry, testing and documentation.

PT141 and PT-141 are names associated with bremelanotide, a cyclic seven-residue peptide. Its identity includes an acetylated amino terminus and a free-acid carboxyl terminus, alongside the ring connection.

PT-141 names and structural notation

The supplied report names PT-141 and bremelanotide together. The existing DailyMed source’s chemical-description section prints the cyclic structure, formula and molecular weight below. Those fields describe the specified reference structure.PT-141 10 mg report: MA-PT1-0037 (opens in a new tab)DailyMed: bremelanotide chemical description, section 11 (opens in a new tab)

Bremelanotide structural reference
FieldReference or document detail
NamesPT141; PT-141; bremelanotide
Sequence and ring notationAc-Nle-cyclo-(Asp-His-D-Phe-Arg-Trp-Lys)-OH
Residues7
Terminal groupsN-acetyl; free-acid C-terminus
Peptide formulaC50H68N14O10
Molecular weight1025.2 g/mol for the peptide moiety
Acetate representation in sourceC50H68N14O10 · xCH3COOH, with 1 ≤ x ≤ 2
CAS number189691-06-3 (PubChem registry number for bremelanotide, PT-141); not verified for the supplied acetate form, which the report does not state
DailyMed: bremelanotide chemical description, section 11 (opens in a new tab)PT-141 10 mg report: MA-PT1-0037 (opens in a new tab)

Keep the ring and salt fields separate

The displayed cyclo notation identifies the ring-containing portion of the molecule. The Nle residue, D-Phe designation and terminal groups remain part of the full specification. The accompanying acetate notation adds a separate chemical-form field; it does not replace the peptide structure.DailyMed: bremelanotide chemical description, section 11 (opens in a new tab)

The source reports the peptide molecular weight separately from the variable acetate term. Retain that basis rather than presenting 1025.2 as a complete formula weight for every acetate composition.DailyMed: bremelanotide chemical description, section 11 (opens in a new tab)

What the supplied report establishes on paper

Report MA-PT1-0037, revision 01, identifies lot PT1-37-TNE as lyophilised PT-141/bremelanotide and records reference matching by LC-HRMS. It does not print the full structural specification or a counterion ratio. The public chemical description and the sample report therefore provide different parts of the identity record.PT-141 10 mg report: MA-PT1-0037 (opens in a new tab)

Request the complete reference specification to link them: residue order, ring connectivity, terminal groups and chemical form. Keep the lot-specific content and chromatographic results alongside that identity record.PT-141 10 mg report: MA-PT1-0037 (opens in a new tab)DailyMed: bremelanotide chemical description, section 11 (opens in a new tab)

Product and certificate checks

Sources and further detail

  1. PT-141 10 mg report: MA-PT1-0037 (opens in a new tab)

    Supplied PDF re-read on 3 October 2026. Identity wording and document-specific results are transcribed; this is not independent authentication.

  2. DailyMed: bremelanotide chemical description, section 11 (opens in a new tab)

    Existing primary source rechecked on 3 October 2026 for structure, formula and peptide molecular weight only. The variable acetate term remains explicit.

Revised 3 October 2026 using the existing source dossier and the specified primary identity records. Report values describe the linked samples. Products are for laboratory research use only.

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