Light-exposure stability studies
Assess a photostability experiment through its light source, exposure measurement, comparison samples and analytical coverage.
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Container-specific stability evidence
Check whether a stability result covers the actual container system, including its closure, presentation and material-contact history.
Read the article →Why another peptide’s stability data may not apply
Assess the transferability of a stability finding across molecular identity, formulation, material history and measured outcomes.
Read the article →Peptide hydrolysis during storage
Understand how evidence for peptide-chain cleavage differs from a falling assay result, and why sequence and conditions matter when interpreting storage studies.
Read the article →Oxidative degradation of peptide materials
Read oxidation evidence as a relationship between a defined material, its surrounding formulation and the products actually measured during an experiment.
Read the article →Deamidation as a peptide stability pathway
Interpret deamidation time courses without treating a sequence motif, an apparent plateau or a solid-state comparison as a universal stability prediction.
Read the article →Aspartate isomerisation in peptide degradation
Understand why an ageing peptide can retain its mass while changing its backbone connectivity, and what evidence is needed to assign that change.
Read the article →Disulfide scrambling during material storage
Read evidence for changing disulfide partners during processing and storage, distinguishing rearrangement from simple reduction and from unrelated aggregation.
Read the article →Photodegradation of peptide materials
Understand how light can change peptide materials and why exposure history, molecular structure and later stress affect the interpretation of photodegradation.
Read the article →Peptide aggregation during storage
Distinguish time-dependent peptide assembly from covalent degradation, and assess what a storage experiment actually measured about each process.
Read the article →Surface adsorption and apparent material loss
Interpret time-dependent recovery from stored peptide samples, including selective loss from mixtures and the importance of the sample environment.
Read the article →Metal-catalysed changes in peptide stability
Assess a proposed metal-related degradation mechanism without assuming that detecting a metal proves catalysis or that all metal interactions destabilise peptides.
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