Epithalon, also written Epitalon, is the four-residue peptide Ala–Glu–Asp–Gly, abbreviated AEDG. Epithalamin and Epithalamine refer to a different, complex preparation and should not be used as structural synonyms for that tetrapeptide.
Epithalon identity and spelling variants
The supplied report uses Epitalon and prints AEDG. The original sequence reference uses Epithalon for Ala–Glu–Asp–Gly and distinguishes the complex preparation Epithalamine. The spelled-out sequence provides the clearest link between the two tetrapeptide spellings.Supplied Epitalon 10 mg report — lot EPI-13-BCQ (opens in a new tab)Khavinson, Bondarev and Butyugov (2003) (opens in a new tab)
| Field | Documented detail |
|---|---|
| Tetrapeptide names | Epithalon; Epitalon |
| Sequence | Ala–Glu–Asp–Gly (AEDG) |
| Residue count | 4 |
| Different preparation | Epithalamin / Epithalamine: a complex preparation, not the AEDG structural name |
| CAS number | 307297-39-8 (PubChem registry number for the AEDG tetrapeptide). The supplied report does not print a CAS number. |
| Molecular formula and molecular weight | Not established by the cited identity passages or supplied report |
Keep the complex preparation separate
Kozina and colleagues distinguish the polypeptide preparation Epithalamin from Epitalon’s defined Ala–Glu–Asp–Gly sequence. A record naming that preparation does not, by itself, specify a mass of the individual AEDG molecule.Kozina et al. (2007) (opens in a new tab)
For a supplier or analytical comparison, retain the exact material name and the sequence where supplied. Similar spelling is not sufficient to connect a complex preparation to a certificate for the synthetic tetrapeptide.Kozina et al. (2007) (opens in a new tab)Supplied Epitalon 10 mg report — lot EPI-13-BCQ (opens in a new tab)
What the supplied Epitalon report records
The report for lot EPI-13-BCQ describes a synthetic freeze-dried tetrapeptide with sequence AEDG. It reports an LC-HRMS comparison against a qualified reference and separates chromatographic area purity from measured peptide content.Supplied Epitalon 10 mg report — lot EPI-13-BCQ (opens in a new tab)
The report lists water and residual TFA separately but does not give a complete salt or hydrate composition. Keep those analytical fields and the stated sequence together when requesting a fuller chemical specification.Supplied Epitalon 10 mg report — lot EPI-13-BCQ (opens in a new tab)
Product and certificate documents
Sources and further detail
- Khavinson, Bondarev and Butyugov (2003) (opens in a new tab)
Existing dossier identity passages: AEDG sequence and distinction from the complex preparation only.
- Kozina et al. (2007) (opens in a new tab)
Existing comparison dossier: defined tetrapeptide versus complex preparation only.
- Supplied Epitalon 10 mg report — lot EPI-13-BCQ (opens in a new tab)
Supplied report: identity wording and analytical fields. Results concern the named sample and lot; this is document transcription, not independent authentication.
Identity sources and supplied documents checked for this revision on 3 October 2026. Report transcription is separate from independent authentication. This article has not undergone independent scientific peer review.