AOD9604: peptide sequence, disulfide bond and identity

AOD9604 and AOD-9604 naming, the YLRIVQCRSVEGSCGF sequence, Tyr-hGH177–191 numbering and Cys7–Cys14 disulfide details in the supplied report.

Substantially revised on 3 October 2026 to focus on molecular identity, naming, chemistry, testing and batch documentation.

AOD9604, also written AOD-9604, is the 16-residue peptide YLRIVQCRSVEGSCGF. The supplied report describes a disulfide bond between cysteines 7 and 14, so the bond position belongs beside the sequence in an identity record.

AOD9604 sequence and bond description

Stier, Vos and Kenley use the name Tyr-hGH177–191 and print YLRIVQCRSVEGSCGF. The supplied report repeats that 16-residue sequence and states that its identity assessment included disulfide-linked mapping for Cys7–Cys14.Stier, Vos and Kenley (2013) (opens in a new tab)Supplied AOD9604 5 mg report — lot AOD-30-TY5 (opens in a new tab)

Identity fields in the cited sources
FieldDocumented detail
NamesAOD9604; AOD-9604; Tyr-hGH177–191
SequenceTyr–Leu–Arg–Ile–Val–Gln–Cys–Arg–Ser–Val–Glu–Gly–Ser–Cys–Gly–Phe
One-letter sequenceYLRIVQCRSVEGSCGF
Disulfide linkageCys7–Cys14 in the displayed 16-residue chain
CAS number221231-10-3 (PubChem registry number for AOD9604). The supplied report does not print a CAS number.
Molecular formula and molecular weightNot printed in the supplied report or established by the cited identity passage
Stier, Vos and Kenley (2013) (opens in a new tab)Supplied AOD9604 5 mg report — lot AOD-30-TY5 (opens in a new tab)

Why the name contains two numbering systems

The parent interval 177–191 contains 15 residues when counted inclusively. The Tyr prefix adds an N-terminal tyrosine, giving the displayed chain 16 residues. By contrast, Cys7 and Cys14 identify positions within that displayed chain.Stier, Vos and Kenley (2013) (opens in a new tab)Supplied AOD9604 5 mg report — lot AOD-30-TY5 (opens in a new tab)

A sequence comparison should therefore preserve both the parent-derived name and the actual 16-residue sequence. The supplied report’s disulfide mapping adds a bond description beyond the list of residues.Stier, Vos and Kenley (2013) (opens in a new tab)Supplied AOD9604 5 mg report — lot AOD-30-TY5 (opens in a new tab)

What remains to clarify in the documents

The CAS number above is the public registry entry for AOD9604; the supplied report does not print one, so it identifies the compound rather than this batch. The sequence and disulfide statement remain directly documented.Stier, Vos and Kenley (2013) (opens in a new tab)Supplied AOD9604 5 mg report — lot AOD-30-TY5 (opens in a new tab)

The report records intact-mass LC-HRMS and disulfide-linked mapping for identity, with chromatographic purity and measured content assessed separately. Keep those analytical findings with lot AOD-30-TY5 and its sample description.Supplied AOD9604 5 mg report — lot AOD-30-TY5 (opens in a new tab)

Product and certificate documents

Sources and further detail

  1. Stier, Vos and Kenley (2013) (opens in a new tab)

    Existing source re-read for Tyr-hGH177–191 and the sequence. Its printed CAS identifier is not treated as a verified match to the supplied reference.

  2. Supplied AOD9604 5 mg report — lot AOD-30-TY5 (opens in a new tab)

    Supplied report: identity wording and analytical fields. Results concern the named sample and lot; this is document transcription, not independent authentication.

Identity sources and supplied documents checked for this revision on 3 October 2026. Report transcription is separate from independent authentication. This article has not undergone independent scientific peer review.

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